I find Emacs much easier to use with the Dvorak keyboard layout, but that's its own big argument waiting to happen.
Under Qwerty, most of the common prefix keys (e.g. C-x, C-c, M-x) are scrunched together on the left hand. If you're also using your left hand to press Ctrl (whether on CapsLock or at the bottom left of the keyboard), you're mangling your hand. That's why there's also a right Ctrl key.
FWIW, I sometimes use Page Up/Down and the arrow keys while just reading, but tend to use the Emacs-style navigation shortcuts while actively editing. C-v never made sense to me, either; I'm guessing it's just historical.
Under Qwerty, most of the common prefix keys (e.g. C-x, C-c, M-x) are scrunched together on the left hand. If you're also using your left hand to press Ctrl (whether on CapsLock or at the bottom left of the keyboard), you're mangling your hand. That's why there's also a right Ctrl key.
FWIW, I sometimes use Page Up/Down and the arrow keys while just reading, but tend to use the Emacs-style navigation shortcuts while actively editing. C-v never made sense to me, either; I'm guessing it's just historical.